Clostridium tetani growth and toxin production in the intestines of germfree rats.
نویسندگان
چکیده
Germfree rats were challenged orally and intrarectally with spores of Clostridium tetani. Although C. tetani spores remained viable in the intestinal tract, they were unable to germinate. Germfree rats were then challenged orally with vegetative cells of C. tetani. Vegetative cells were able to colonize the intestinal tract, replicate, and produce toxin. Tetanus antitoxin, but no tetanus toxin, was detected in the sera of monoassociated rats.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 41 2 شماره
صفحات -
تاریخ انتشار 1983